Publications

Mirrashidi KM, Elwell CA, Verschueren e, Johnson JR, Frando A, Von Dollen J, Rosenberg O, Gulbahce N, Jang G, Johnson T, Jager S, Gopalakrishnan AM, Sherry J, Dunn JD, Olive A, Penn B, Shales M, Cox JS, Starnbach MN, Derre I, Valdivia R, Krogan NJ, Engel J. Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. Cell Host Microbe. 2015 Jul 8;18(1):109-21. PMCID: PMC4540348. pubmed

Watson RO, Bell SL, MacDuff DA, Kimmey JM, Diner EJ, Olivas J, Vance RE, Stallings CL, Virgin HW, Cox JS. The Cytosolic Sensor cGas Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy. Cell Host Microbe. 2015 Jun 10;17(6):811-9. PMCID: PMC4466081. pubmed

Rosenberg OS, Dovala D, Li X, Connolly L, Bendebury A, Finer-Moore J, Holton J, Cheng Y, Stroud RM, Cox JS. Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion. Cell. 2015 Apr 23;161(3):501-12. PMCID: PMC4409929. pubmed

Ekiert DC and Cox JS. Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion. Proc Natl Acad Sci USA. 2014 Oct 14;111(41):14758-63. PMCID: PMC4205667. pubmed

Lohse MB, Rosenberg OS, Cox JS, Stroud RM, Finer-Moore JS, Johnson AD. Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi. Proc Natl Acad Sci USA. 2014 Jul 22;111(29):10404-10. PMCID: PMC4115540. pubmed

Zacharia VM, Manzanillo PS, Nair VR, Marciano DK, Kinch LN, Grishin NV, Cox JS, Shiloh MU. cor, a novel carbon monoxide resistance gene, is essential for Mycobacterium tuberculosis pathogenesis. MBio. 2013 Nov 19;4(6):e00721-13. PMCID: PMC3870250. pubmed

Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS. The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature. 2013 Sep 26;501(7468):512-6. PMCID: PMC3886920. pubmed

Eisele NA, Ruby T, Jacobson A, Manzanillo PS, Cox JS, Lam L, Mukundan L, Chawla A, Monack DM. Salmonella require the fatty acid regulator PPARδ for the establishment of a metabolic environment essential for long-term persistence. Cell Host Microbe. 2013 Aug 14;14(2):171-82. PMCID: PMC3785333. pubmed

Stanley SA and Cox JS. Host-pathogen interactions during Mycobacterium tuberculosis infections. Curr Top Microbiol Immunol. 2013;374:211-41. pubmed

Watson RO, Manzanillo PS, Cox JS. Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway. Cell. 2012 Aug 17;150(4):803-15. PMCID: PMC3708656. pubmed

Manzanillo PS, Shiloh MU, Portnoy DA, Cox JS. Mycobacterium tuberculosis acticates the DNA-dependent cytosolic surveillance pathway within macrophages. Cell Host Microbe. 2012 May 17;11(5):469-80. PMCID: PMC3662372. pubmed

Chow ED and Cox JS. TB lipidomics–the final frontier. Chem Biol. 2011 Dec 23;18(12):1517-8. PMCID: PMC3661412. pubmed

Rosenberg OS, Dovey C, Tempesta M, Robbins RA, Finer-Moore JS, Stroud RM, Cox JS. EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins. Proc Natl Acad Sci USA. 2011 Aug 16;108(33):13450-5. PMCID: PMC3158157. pubmed

Ohol YM, Goetz DH, Chan K, Shiloh MU, Craik CS, Cox JS. Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence. Cell Host Microbe. 2010 Mar 18;7(3):210-20. PMCID: PMC3121311. pubmed

More

UC Berkeley